About NADPrime & Our Review Method
Editorial policy updated: September 22, 2026
NADPrime is an affiliate-supported research and comparison site. We translate published human evidence, product labels, manufacturer disclosures and return terms into practical comparisons. We do not present an invented clinician, personal tester or professional credential as authority.
What NADPrime is - and is not
NADPrime covers NAD+ precursors and selected healthy-aging supplements for readers who want a clearer separation between clinical evidence and sales claims. The site is educational, not a medical service, and it does not diagnose symptoms, prescribe doses or replace a clinician.
How we research a product
We prioritize: (1) peer-reviewed human studies on the complete formula when they exist; (2) human studies on the same ingredient and relevant form; (3) the current product label and manufacturer disclosures; (4) publicly available testing documents such as Certificates of Analysis; and (5) current refund and purchase terms. Ingredient studies are never presented as if they prove the finished formula.
How we score
| Factor | What we evaluate |
|---|---|
| Human evidence | Strength, relevance and limitations of formula-specific or ingredient-level studies. |
| Transparency | Whether the label gives usable amounts and whether testing documents are available. |
| Marketing-evidence fit | Whether promotional claims stay within what the evidence can reasonably support. |
| Practical use | Routine complexity, label clarity and how easy the product is to evaluate against the research. |
| Return terms | Current manufacturer refund window and material conditions; this is a risk-management factor, not evidence that a product works. |
Scores are NADPrime editorial scores. They are not consumer star averages, clinical effectiveness grades or medical recommendations.
Affiliate independence
Some outbound links are affiliate links. If a purchase is attributed to one of those links, NADPrime may earn a commission at no extra cost to the reader. That commercial relationship is disclosed, and it does not turn a manufacturer claim into evidence. We include limitations, negative findings and reasons to skip a product when the record supports them.
Corrections and evidence updates
Supplement labels, guarantees and research can change. Pages show an update date, and we revise them when a meaningful source changes. If you find an error or a study we missed, contact us with the source so we can review it.
Medical scope
Common concerns such as fatigue, sleep changes, low libido, brain fog or slower recovery are nonspecific. They should not be used to self-diagnose "low NAD+", growth-hormone deficiency or testosterone deficiency. Persistent or concerning symptoms deserve appropriate medical evaluation.